Metabolomics in Molecular Medicine - from idea to data interpretation, 30 September - 2 October 2024

A jointly organized workshop by the Swedish Metabolomics Centre (SMC) and FIMM's Metabolomics Unit - University of Helsinki providing an introduction to different aspects of metabolomics, from experimental design to data analysis. The programme consists of a public symposium on the first day and practical elements for workshop participants on days 2-3. Workshop participants are also expected to attend the symposium on the first day.

Please see the bottom of the page for the registration forms for the workshop and the symposium. The registration deadline for the workshop has been extended, and is now 9 August 2024.

Metabolomics measures small molecules commonly known as metabolites that all together comprise a metabolome of a biological system. Since metabolome is a reflection of physiological status, metabolomics helps us to understand molecular mechanisms such as drug responses and to find new indicators for diseases.

This workshop provides an introduction to mass spectrometry-based metabolomics with a special focus on its applications in molecular medicine. The workshop starts with a mini-symposium where the experts in the field discuss the recent advancements and applications in metabolomics research in life sciences. The following two days of practical training will cover the metabolomics workflow from the principles of experimental design, sample preparation, theory of chromatographic separation and mass spectrometry to data acquisition, pre-processing, analysis and interpretation.

Preliminary schedule

Monday 30/9 - Public symposium on “Metabolomics in Molecular Medicine”, lecture room Carl Kempe, KBC

09:00-10:00 Registration and fika
10:00-10:15 Welcome and opening words
10:15-11:15 Keynote: Thomas Moritz, Center for Basic Metabolic Research, University of Copenhagen - Metabolomics for studying metabolism: from technology to applications
11:15-12:15 Keynote: Michael Zimmermann, European Molecular Biology Laboratory, Heidelberg - Employing metabolomics to unravel microbiome-host interactions
12:15-13:15 Lunch
13:15-14:15 Keynote: Anni Nieminen, Institute for Molecular Medicine Finland (FIMM), University of Helsinki - Advancing the understanding of molecular phenotypes through Fluxomics
14:15-15:15 Keynote: Ujjwal Neogi, Karolinska Institute - Integrative omics to identify the virus-host immunometabolic footprint during infection
15:15-15:30 Closing words

15:30 Laboratory tour

In the evening: Dinner for workshop participants and keynote speakers

Tuesday 1/10 - Workshop day 1 – Metabolomics and Mass Spectrometry: Theory and Practice

08:30-12:00 Morning session

• Introduction to Metabolomics and Lipidomics
• Metabolite extraction
• Mass spectrometry: Theory

12:00-13:00 Lunch

13:00-17:00 Afternoon session

• Mass spectrometry: Practical session
• Fluxomics

Wednesday 2/10 - Workshop day 2 - Data processing and interpretation

08:30-12:00 Morning session

• Data pre-processing
• Chemometrics

12:00-13:00 Lunch

13:00-14:30 Afternoon session

• Normalizations and statistical know-how in the field

The keynote speakers as well as the exact schedule for the workshop days will be updated on this page as the workshop planning progresses.

Practical information

Level: Master's student/PhD student/Postdoc/Research Engineer

Language: English

Qualifications required: In case of a large number of applications for the workshop, preference will be given to participants from member institutes of the Nordic EMBL Partnership in Molecular Medicine, and EMBL.

Number of participants: 15 – 20

Umeå University will provide successful participants with a certificate and a recommendation for 1.0 ECTS, if necessary.

This Metabolomics workshop is part of the NordForsk-funded Infrastructure Hub of the Nordic EMBL Partnership for Molecular Medicine.

Application deadline for attending the workshop is 9 August 2024.
Registration deadline for the symposium is 13 September 2024.