This event is a forum where people from industry, academia and research infrastructures can meet and discuss the latest developments in Applied Mass Spectrometry. The event consists of several workshops, a conference and a fair where leading companies in the field will present their latest analytical applications and technologies.
This event includes a workshop day on 19 March and a conference and a fair on 20 March. The event ends with a dinner on 20 March.
Note! The programme is under construction and subject to change
09:00 – 10:30 at Glasburen, KBC: Workshop by Agilent, "Agilent MassHunter, your trusted answer for analyte identification and quantification"
Teacher: James Waddington, PhD, LC-MS Application Engineer, Agilent, UK
Abstract: Tired of the unknown? In this expert led workshop we will showcase how the Agilent MassHunter software suite can simplify your day-to-day lab operation and data analysis, leaving you time to focus on other things in the lab that matter. We will cover a range of topics, focussed on Life Science research, from data acquisition to statistical analysis. Throughout the interactive session we will aim to cover a range of applications, sharing hints and tips on how to get the best data possible from your samples. Whether you’re interested in metabolites, lipids, peptides or proteins, we’ve got a solution for you.
The workshop will be focussed on the analysis of high-resolution accurate mass (HRAM) data from our range of LC-QTOF instrumentation. Automated workflows to turn your spectra into compounds will be shown, with the help of our powerful library management software ChemVista. We know that identification is often only one part of the story, with quantification a key component of any experiment. Quantitative analysis tailored to you will be demonstrated, with streamlined approaches to speed up your analysis described. Finally, user-friendly downstream statistical data analysis will also be explored using our latest addition to the suite, MassHunter Explorer.
We invite scientists and technicians from all levels of expertise to join us. Better yet, our Application Specialist will be on hand to answer any specific questions you have throughout the day.
Literature for further reading:
MassHunter Masterclass Webinar Series: https://lnkd.in/dH5wrWR3
MassHunter software suite: https://www.agilent.com/cs/library/brochures/brochure-masshunter-software-5994-4923en-agilent.pdf
MassHunter Explorer: https://www.agilent.com/cs/library/brochures/masshunter-explorer-5994-6107en-agilent.pdf
ChemVista: https://www.agilent.com/cs/library/brochures/br-chemvista-software-5994-5965en-agilent.pdf
10:30 – 12:00 at Stora Fokusrummet (KBF301), KBC: Workshop by Teknolab Sorbent AB and Extraction Technologies Norway AS, "Electromembrane Extraction (EME) – New technology for green efficient and highly selective sample preparation of biological samples"
Teacher: Professor Stig Pedersen-Bjergaard, Section for Pharmaceutical Chemistry, University of Oslo, Norway
Abstract: This course offers a comprehensive introduction to electromembrane extraction (EME), a recently commercialized and innovative addition to the analytical chemistry toolbox. EME is a microextraction technique applicable for acids, bases, and permanently ionic compounds. It involves the extraction of target analytes from an aqueous sample, across a liquid membrane, and into an acceptor solution, all facilitated by an external electrical field. The liquid membrane consists of a few microliters of organic solvent immobilized within the pores of a filter membrane, while the acceptor solution is a microliter volume of pure aqueous buffer.
EME stands out for its unique selectivity, which can be fine-tuned by adjusting the direction and magnitude of the electrical field, the chemical composition of the liquid membrane, and pH. As a green approach to sample preparation, EME minimizes the use of solvents and chemicals. It provides efficient cleanup of complex samples such as blood, and the aqueous acceptor solutions can be directly injected into LC/LC-MS systems without further processing.
This course will focus on introducing the fundamental principles of EME, covering method development, applications, advantages, and limitations, as well as its potential as a cutting-edge sample preparation technique. It is ideal for those interested in eco-friendly sample preparation methods and pioneering research into emerging concepts and technologies. With the growing importance of green sample preparation and the availability of commercial equipment, EME offers a sustainable alternative for scientists. Innovative research related to EME is expected to increase in the future, due to the unique flexibility of the concept. Understanding the basics of EME, as given in this short course, is a major advantage both in the green and innovative direction.
In this workshop, you will get to know:
• The EME principle
• How to develop an EME method
Be the first in Sweden to get knowledge and experience about EME!
References for further reading:
ETN, Electromembrane extraction (EME) vs. SPE and LLE. 2024 Oct 7. https://cdn.prod.website-files.com/5eb27d32b7f1ceff62ec3965/671fba7910f66ec199875276_EME%20vs%20SPE%20and%20LLE.pdf
Oldeide Hay A, Trones R, Herfindal L, Skrede S, Hansen FA. Determination of methotrexate and its metabolites in human plasma by electromembrane extraction in conductive vials followed by LC-MS/MS. Advances in Sample Preparation, 2: 100011. https://doi.org/10.1016/j.sampre.2022.100011.
Schüller M, Bergh MS, Pedersen-Bjergaard S, Øiestad EL. Electromembrane extraction of drugs of abuse and prescription drugs from micropulverized hair. J Anal Toxicol. 2024 Aug 21;48(7):489-498. doi: 10.1093/jat/bkae051. PMID: 38905017; PMCID: PMC11336399.
Skaalvik TG, Øiestad EL, Pedersen-Bjergaard S, Hegstad S. Determination of amphetamine enantiomers in urine by conductive vial electromembrane extraction and ultra-high performance supercritical fluid chromatography tandem mass spectrometry. Drug Test Anal. 2023 Aug;15(8):909-918. doi: 10.1002/dta.3487. Epub 2023 May 10. PMID: 37114617.
Please check also out the ETN webpage about how to do EME at: https://how-to-eme.com/
If you are interested in more publications about EME, please also have a look at our list of selected publications on our home page at: https://www.etn-eme.com/publications
12:00 – 13:00 Lunch break. The organizers do not provide lunch.
The organizers do not provide lunch.
13:00 – 16:00 at Stora Fokusrummet (KBF301), KBC: Workshop by the SMC and Umeå University Library in collaboration with EMBL-EBI, "A hands-on guide to MetaboLights at EMBL-EBI and how it can help you as a researcher in metabolomics to comply with Open Science policies"
Teachers:
Online: Noemi Tejera, European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, UK
Online: Ozgur Yurekten, European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, UK
On-site: Annika Johansson, Swedish Metabolomics Centre, Department of Plant Physiology, Umeå University, Sweden
On-site: Theresa Kieselbach, Umeå University Library, Umeå University, Sweden
Note: This workshop includes a coffee break.
Abstract: This workshop will give you an introduction to Open Science policies and the FAIR-data principles and how you can take advantage of the MetaboLights repository at EMBL-EBI to put them into practice, if you do research in metabolomics.
The workshop consists of three parts that include:
This workshop is relevant for everybody who wants to give access to research data from metabolomics experiments to meet Open Science requirements by a funder, a journal or a research organization. It includes a hands-on part to learn how to prepare data and metadata from metabolomics experiments for submission to MetaboLights. It does not matter if you already have data from existing metabolomics experiments or if you are going to create such data in your future research. In either case this workshop will give you help to get started and to proceed on your own.
References for further reading:
Swedish University of Agricultural Sciences. (2022). Policy on the management of and open access to research and environmental monitoring and assessment data at SLU. URL: https://www.slu.se/en/subweb/library/publish-and-analyse/archiving-and-publishing-research-data/slus-datahanteringspolicy/
Umeå University. (2021). Research data policy. Reg. no.: FS 1.1.-545-21. URL: Reg. no.: FS 1.1.-545-21. URL: https://www.umu.se/en/legal-framework/research/research-data-policy/
Yurekten, O., Payne, T., Tejera, N., Amaladoss, F. X., Martin, C., Williams, M., & O'Donovan, C. (2024). MetaboLights: open data repository for metabolomics. Nucleic acids research, 52(D1), D640–D646. https://doi.org/10.1093/nar/gkad1045
MetaboLights online tutorial ‘Quick tour’. URL: https://www.ebi.ac.uk/training/online/courses/metabolights-quick-tour/. https://doi.org/10.6019/TOL.MbL-qt.2012.00001.1
9:00 – 16:30 Conference in the Carl-Kempe Hall (KBE303) and fair in KBC Glasburen and the KBC Hall
9:00 The reception desk opens in the KBC Hall.
10:15 – 10:20 Jonas Bergquist, SMSS. Welcome speech.
10:20 – 10:55 Anders Feldthus and Deepak Luthra, Agilent Nordics. PFAS analysis by GC-MS and LC-MSMS. Accurate quantification at trace level in different matrices
10:55 – 11:30 Noud van der Borg, Bruker Netherlands. Fast screening and quantification of seized drugs.
11:30 – 12:05 Ross Chawner, Waters. Rapid Data Rationalization for Biotransformation using the Xevo MRT Mass Spectrometer with Dedicated Data-Mining Software.
12:05 – 13:35 Lunch break and opportunity to visit the fair and to talk to the representatives of the companies.
13:35 – 14:10 Tony Wiklund, Thermo Fisher Scientific Sweden. Thermo Fisher innovation - How can you bridge the gap between discovery and the clinic?
14.10 – 14:45 Magnus Olin, Shimadzu Sweden. OAD – Oxygen attachment dissociation – A novel, unique, selective MS/MS fragmentation technology that specifically fragments at a C=C bond position.
14:45 – 15:15 Coffee break and opportunity to visit the fair and to talk to the representatives of the companies.
15:15 – 15:50 Anders Dahl Knudsen, Sciex Sweden. SCIEX Advances in Mass Spectrometry for Metabolomics – 7500+, ZenoTOF and EAD fragmentation.
15:50 – 16:25 Sebastiano Panto, LECO Germany. Non-Targeted Analysis using comprehensive-two-dimensional gas chromatography coupled to a mass spectrometry.
16:25 – 16:30 Theresa Kieselbach , SMSS. Closing speech.
Dinner after the event
You are welcome to come for dinner at a restaurant after the meeting. The costs for this dinner are not covered by the conference, and you must pay for them privately.
Important dates:
Monday, 3 March at 23:59 - registration deadline for participation in the Workshops on 19 March
Thursday, 6 March at 23:59 - registration deadline for participation in the Conference and Fair on 20 March.
After 6 March, you can register for the Conference, but not for the lunch.
Registration form
Registration fee and processing of personal data
Attending the conference, the workshops and the fair is free of charge, but you have to register for it. The conference includes lunch and coffee, but if you want to participate in the dinner on March 20, you pay for it privately.
If you register for this conference and one or more of its workshops, you agree that the organizers at Umeå University and at the SMSS collect and process your personal data to register you for this conference and to provide all registered participants with a participant list that contains their names affiliations and contact details.
Chemical Biological Centre, KBC-building, at Umeå University.
If you have not been to KBC before, please have a look at the digital campus map (https://www.umu.se/en/contact-us/maps/digital-maps/). You can easily go to the KBC building from the city center of Umeå by bus. Take bus 5 or 8 from Vasaplan and get off at the bus stop Växthuset. From there, it is only a few minutes to walk to get to the KBC Building. You can find more information about timetables at: https://www.tabussen.nu/en/. If you arrive by plane to Umeå, the fastest way to get to the KBC Building is taking a taxi. The journey takes approximately 20 minutes. Please book your taxi in advance to avoid waiting at the airport.
The event is organized by the Swedish Mass Spectrometry Society (SMSS), the Swedish Metabolomics Centre (SMC), and SciLifeLab in collaboration with the Mass Spectrometry Network Umeå and the participating companies. The KBC Communications Office and staff at Umeå University Library provide organisational support.
